Rapid Response Report: Peer-Reviewed Summary with Critical Appraisal Epidermal Growth Factor Receptor Mutation Analysis in Advanced Non-Small Cell Lung Cancer: Review of Economic Evaluations and Framework for Economic Analyses
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چکیده
Agence canadienne des médicaments et des technologies de la santé Supporting Informed Decisions
منابع مشابه
Expression of Epidermal Growth Factor Receptor and the association with Demographic and Prognostic Factors in Patients with Non-small Cell Lung Cancer
Introduction: Growth, proliferation, survival, and differentiation are the prominent characteristics of cells, which are affected by cancer. Epidermal growth factor receptor (EGFR) plays a pivotal role in the effective control of these features. Given the significance of EGFR signaling pathway in non-small cell lung cancer (NSCLC), EGFR expression is influential on these cell characteristics. I...
متن کاملEpidermal Growth Factor Receptor (EGFR) Gene Mutation Analysis in Adenocarcinoma of Lung, the First Report from Iran
Background and Objective: Epidermal growth factor receptor (EGFR) gene mutation, especially in exons 18 to 21, is an important predictor of the response rate of lung adenocarcinoma to tyrosine kinase inhibitors. There are variable reports from Asian and European countries, as well as North America, about the frequency of the EGFR mutation in lung adenocarcinoma, yet molecular s...
متن کاملTITLE: Epidermal Growth Factor Receptor Mutation Analysis in Advanced Non-Small Cell Lung Cancer: Review of Economic Evaluations and Framework for Economic Analyses
This document is prepared by the Health Technology Inquiry Service (HTIS), an information service of the Canadian Agency for Drugs and Technologies in Health. The service is provided to those involved in planning and providing health care in Canada. HTIS responses are based on a comprehensive and systematic search of literature available to CADTH at the time of preparation. The intent is to pro...
متن کاملAssessment of epidermal growth factor receptor status in glioblastomas
Objective(s): Our previous study showed that a newly designed tracer radioiodinated 6-(3-morpholinopropoxy)-7-ethoxy-4-(3'-iodophenoxy)quinazoline ([125I]PYK) is promising for the evaluation of the epidermal growth factor receptor (EGFR) status and prediction of gefitinib treatment of non-small cell lung cancer. EGFR is over-expressed and mutated also in glioblastoma. In the present study, the ...
متن کاملمقایسه تأثیر شیمی‌درمانی استاندارد و اثر ترکیبی آن با Cetuximab بر میزان بقاء در مبتلایان به سرطان پیشرفته کولون
Background and Aim: Recent advances in molecular and cellular biology and the importance of Epidermal growth factor receptor(EGFR) in the development and progression of many solid malignancies such as Colorectal Cancer (CRC) and non- small cell lung cancer have allowed rapid advances in rational drug design and targeted therapies for malignancies.Cetuximab or Erbitux, an IgG1 monoclonal antib...
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تاریخ انتشار 2010